Synthesis of (-)-epibatidine.
نویسندگان
چکیده
The synthesis of (-)-epibatidine has been accomplished utilizing a highly exo-selective asymmetric hetero Diels-Alder reaction. The key steps employed to transform the resulting bicycle into the natural product include a fluoride-promoted fragmentation and a Hofmann rearrangement. Reaction: see text.
منابع مشابه
Chemoenzymatic formal synthesis of (-)- and (+)-epibatidine.
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ورودعنوان ژورنال:
- Organic letters
دوره 3 19 شماره
صفحات -
تاریخ انتشار 2001